Environmental pollution outweighs the global obesity epidemic, according to new scientific analysis.
The toxin is “Obesogen“The body may change the way it regulates weight, but it’s not yet widely accepted, but hundreds of scientists in the review claim that the evidence is now as solid as it should be. There is.
(Photo: (Photo by Jeff J Mitchell / Getty Images))
The most disturbing factor in the findings is that some of the chemical effects that cause weight gain can be passed on from generation to generation by altering genetic function. Researchers attribute obesity to contaminants such as plastics, pesticides, flame retardants, and bisphenol A (BPA), which is widely used in air pollution.
Global obesity since 1975 4 timesMore people are obese or overweight than underweight and are increasing in all countries analyzed. Nearly 2 billion and 40 million children under the age of 5 are overweight or overweight.
“The focus of clinical people is on calories-if you burn more calories, you will gain weight,” says former director Dr. Gerold Heindel. National Institute of Environmental Health Sciences Lead author of one of the three review studies.
“If that works, we should see a reduction in obesity,” he added. “But we are not. Obesity is on the rise, especially among young people. The real question is why people eat more. The obesity paradigm focuses on this, and studies have focused on these. It suggests that the substance is the cause. “
In addition, researchers say, this strategy can prevent obesity, especially by limiting contaminated exposure to pregnant women and newborns.
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Various support studies
More than 40 experts have submitted three review articles to the peer-reviewed journal Biochemical Pharmacology, highlighting 1,400 findings in support of obesity. According to researchers, these compounds can be found in water and dust, food packaging, personal hygiene products, household cleansers, furniture, and electronic devices.
Based on human cell and animal studies and people’s epidemiological studies, the study lists approximately 50 substances as having solid evidence of obesity-inducing effects. Examples are phthalates, which are BPA and other plastic components. A 2020 review of 15 studies showed that 12 of them had a substantial relationship between BPA levels and adult obesity.
Pesticides such as DDT and tributyltin, old flame retardants and new alternatives, dioxins, PCBs and air pollution are all obese substances. Several recent studies have linked childhood exposure to filthy air to obesity.
In this assessment, PFAS compounds are also labeled as obese because they last for a long time in the environment. These are included in food packaging, kitchen utensils, furniture, and some child seats. According to a two-year randomized clinical study published in 2018, people with the highest PFAS levels, especially women, gained weight after a diet.
Weight gain is a documented side effect of some antidepressants. “This is a proof of the principle. Drugs designed for a certain purpose can cause side effects that interfere with metabolism,” Heindel added. Some artificial sweeteners and triclosan, an antibacterial compound that was partially banned in the United States in 2017, were also obese.
Studies show that obesity works by destroying the body’s “metabolic thermostats,” making it easier to gain weight and more difficult to lose weight. Hormonal interactions from adipose tissue, stomach, pancreas, liver, and brain help the body regulate energy intake and consumption through exercise.
Pollutants and body fat
According to researchers, contaminants directly affect the number and size of fat cells and can disrupt the signals that make an individual feel full, thyroid function, and the dopamine reward system. They can also affect the gut microbiota and promote weight gain by increasing the efficiency of absorbing calories from the gut.
“We have four or five substances that cause epigenetic obesity across generations,” Heindel added, referring to genetic changes in gene expression. Although her granddaughter was not physically exposed to currently banned chemicals, a 2021 study found that obesity in women was highly associated with the degree of DDT exposure of her grandmother. became.
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